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Domperidone is used to relieve nausea and vomiting, which are symptoms of an upset stomach. It can also help with stomach discomfort by speeding up the movement of food through the stomach. Omeprazole is used to treat acid reflux, which is when stomach acid flows back into the esophagus causing heartburn, and stomach ulcers, which are sores in the stomach lining. Both medicines aim to relieve discomfort in the digestive system, but they target different causes of that discomfort.
Domperidone works by blocking dopamine receptors, which are proteins in the brain that can trigger nausea, in the gut to increase the movement of the stomach and intestines. Omeprazole is a proton pump inhibitor, which is a type of drug that reduces the amount of acid produced in the stomach by blocking the enzyme in the stomach wall that produces acid. Both medicines help with digestive issues, but they do so in different ways.
The usual adult daily dose for Domperidone is typically 10 mg taken up to three times a day, and it should be taken before meals for best results. Omeprazole is usually taken as 20 mg once a day and can be taken with or without food, but it is often recommended to take it before a meal for optimal effect. Both medicines are taken orally, which means by mouth.
Domperidone can cause side effects like dry mouth, headache, and dizziness. A significant adverse effect is an irregular heartbeat, which refers to an abnormal heart rhythm. Omeprazole may cause headaches, stomach pain, and nausea. A serious adverse effect is a risk of bone fractures, which means broken bones, especially with long-term use. Both medications can cause headaches and dizziness, which refer to a feeling of lightheadedness.
Domperidone should not be used by people with heart conditions, as it can cause serious heart rhythm problems, and it is also not recommended for those with liver problems. Omeprazole should be used cautiously by people with liver disease and may cause kidney issues. Both medications can interact with other drugs, so it's important to inform your doctor about all medications you are taking. They share the common attribute of potentially causing allergic reactions, which can include symptoms like rash, itching, or swelling.
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