fluconazole

ENGLISH

Synonyms

Approved Treatment Indication:

Candidiasis, Chronic Mucocutaneous, Coccidioidomycosis, Histoplasmosis, Candidiasis, Oral, Candidiasis, Vulvovaginal, Pneumonia, Blastomycosis, Fungemia, Urinary Tract Infections

Summary

  • What conditions Fluconazole is used for

    Fluconazole is used to treat fungal infections, which include yeast infections, thrush, and certain types of meningitis, which is an inflammation of the protective membranes covering the brain and spinal cord.

  • How Fluconazole works in the body

    Fluconazole works by inhibiting an enzyme that fungi need to grow, which stops the fungi from multiplying and allows your body's immune system to eliminate the infection.

  • The usual dosages and routes of administration of Fluconazole

    The usual starting dose for adults is 150 mg as a single dose for vaginal yeast infections. For other infections, the dose may vary, and it can be taken with or without food.

  • The most commonly observed adverse effects of Fluconazole

    Common side effects include headache, nausea, and stomach pain, which are usually mild and temporary.

  • Important safety warnings and contraindications of Fluconazole

    Fluconazole can cause liver damage and serious skin reactions. It is not recommended for people with certain heart conditions due to the risk of heart rhythm problems.

Drug Status

Government Approvals

Government Approvals

US(FDA), UK(BNF)

WHO Essential Medicine

WHO Essential Medicine

YES

Known Teratogen

Known Teratogen

NO

Pharmaceutical Class

Pharmaceutical Class

Azole Antifungal

Controlled Drug Substance

Controlled Drug Substance

NO

Indications and Purpose

  • What is Fluconazole?

    Fluconazole is an antifungal medication used to treat infections caused by fungi, such as yeast infections and thrush. It works by stopping the growth of fungi. Fluconazole is often used alone but can be part of a combination therapy for certain conditions.
  • How does Fluconazole work?

    Fluconazole works by inhibiting an enzyme that fungi need to grow. This stops the fungi from multiplying, allowing your body's immune system to eliminate the infection. Think of it like cutting off the power supply to a machine, causing it to stop working.
  • Is Fluconazole effective?

    Fluconazole is effective in treating fungal infections like yeast infections and thrush. It works by stopping the growth of fungi. Clinical studies support its effectiveness for these conditions. Always follow your doctor's instructions for the best results.

Directions for Use

  • What is the usual dose of Fluconazole?

    The usual starting dose of Fluconazole for adults is 150 mg as a single dose for vaginal yeast infections. For other infections, the dose may vary. Your doctor will adjust the dose based on your specific condition and needs. Always follow your doctor's dosing instructions.
  • How do I take Fluconazole?

    Fluconazole is usually taken as a single dose, but your doctor may adjust this based on your condition. You can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Then, skip the missed dose and continue your normal schedule. Never take two doses at once. Always follow your doctor's specific instructions.
  • For how long do I take Fluconazole?

    Fluconazole is usually taken for short-term treatment of fungal infections. The duration depends on the type and severity of the infection. Always follow your doctor's instructions on how long to take the medication. Stopping early can lead to the infection returning.
  • How long does it take for Fluconazole to start working?

    Fluconazole starts working within a few hours, but it may take a few days to see full improvement in symptoms. The time it takes to work can depend on the type and severity of the infection. Always take it as prescribed for the best results.
  • How should I store Fluconazole?

    Store Fluconazole at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children. Check the expiration date regularly and dispose of any unused or expired medication properly.
  • How do I dispose of Fluconazole?

    Bring unused Fluconazole to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.

Warnings and Precautions

  • Who should avoid taking Fluconazole?

    Don't take Fluconazole if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. It's also not recommended for people with certain heart conditions due to the risk of heart rhythm problems. Always consult your doctor about any concerns.
  • Can I take Fluconazole with other prescription drugs?

    Fluconazole can interact with several medications, increasing the risk of side effects. For example, it can increase the levels of certain drugs like warfarin, which is a blood thinner, leading to bleeding risks. Always inform your doctor about all medications you're taking to avoid interactions.
  • Can Fluconazole be taken safely while pregnant?

    Fluconazole isn't recommended during pregnancy, especially in high doses. It may cause birth defects. If you're pregnant or planning to become pregnant, talk with your doctor about safer treatment options. Your doctor can help create a pregnancy-specific treatment plan.
  • Can Fluconazole be taken safely while breastfeeding?

    Fluconazole is generally considered safe while breastfeeding in low doses. It does pass into breast milk, but adverse effects on the infant are rare. Always talk with your doctor about the risks and benefits of taking Fluconazole while breastfeeding.
  • Is Fluconazole safe for the elderly?

    Older people's kidneys might not work as well as younger people's, so they may need a lower dose of fluconazole. Doctors should check how well their kidneys are working and adjust the medicine amount accordingly. While fluconazole is usually safe, some older patients have had more problems like low blood counts (anemia) and kidney failure, but it's not certain if the medicine caused these issues.
  • Is it safe to exercise while taking Fluconazole?

    You can exercise while taking Fluconazole. This medication doesn't typically limit exercise capacity. However, if you feel dizzy or unwell during physical activity, slow down or stop and rest. Talk with your doctor if you have concerns about exercising while on this medication.
  • Is it safe to drink alcohol while taking Fluconazole?

    It's best to avoid alcohol while taking Fluconazole. Alcohol can increase the risk of liver damage, which is a potential side effect of Fluconazole. If you choose to drink, do so in moderation and watch for symptoms like nausea or yellowing of the skin. Talk with your doctor for personalized advice.
  • What are the most common side effects of Fluconazole?

    Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Fluconazole include headache, nausea, and stomach pain. These effects vary from person to person. If you notice new symptoms after starting Fluconazole, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
  • Does Fluconazole have adverse effects?

    Adverse effects are unwanted reactions to a medication. Common adverse effects of Fluconazole include nausea, headache, and stomach pain. Serious effects like liver damage or severe skin reactions are rare but require immediate medical attention. Always tell your doctor about any new or worsening symptoms while taking Fluconazole.
  • Is Fluconazole addictive?

    Fluconazole is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Fluconazole doesn't carry this risk.
  • Does Fluconazole have any safety warnings?

    Fluconazole has important safety warnings. It can cause liver damage, so watch for symptoms like yellowing of the skin or eyes. It may also cause serious skin reactions. If you experience a rash, stop taking the medication and seek medical help. Always follow your doctor's advice and report any unusual symptoms.
  • Is it safe to stop Fluconazole?

    Fluconazole is often used for short-term treatment of infections. Stopping it early can lead to the infection returning or worsening. Always complete the full course as prescribed by your doctor. If you have concerns about stopping Fluconazole, talk with your doctor for guidance.

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