gentamicin (ophthalmic)
ENGLISH
Synonyms
Approved Treatment Indication:
Escherichia coli Infections, Bacterial Eye Infections, Bacterial Skin Diseases, Proteus Infections, Serratia Infections, Infectious Bone Diseases, Pseudomonas Infections, Sepsis, Staphylococcal Infections, Central Nervous System Infections, Urinary Tract Infections, Respiratory Tract Infections, Endocarditis, Klebsiella Infections, Soft Tissue Infections, Tuberculous Peritonitis
Summary
What conditions is gentamicin used for?
Gentamicin is used to treat serious bacterial infections, which are illnesses caused by harmful bacteria. It is effective against infections in the urinary tract, respiratory system, and skin. This medication is often administered in hospitals due to its potency and is typically given by injection.
How does gentamicin work in the body?
Gentamicin works by stopping bacteria from making proteins they need to grow, which are essential molecules for their survival. It binds to bacterial ribosomes, which are structures that make proteins, and disrupts their function. This action kills the bacteria, helping to clear the infection.
What are the usual dosages and routes of administration for gentamicin?
Gentamicin is usually given as an injection by a healthcare professional. The dose and frequency depend on the infection being treated and the patient's kidney function. It's important to follow your doctor's instructions carefully to ensure effective treatment.
What are the most commonly observed adverse effects of gentamicin?
Common side effects of gentamicin include kidney damage and hearing loss, which are serious conditions that require monitoring. Less common effects include dizziness and balance issues. If you notice any new or worsening symptoms, contact your doctor immediately.
What are important safety warnings and contraindications for gentamicin?
Gentamicin can cause kidney damage and hearing loss, especially with high doses or prolonged use. Monitoring kidney function and hearing is essential. It should not be used if you have a known allergy to it. Caution is needed in patients with kidney problems or hearing issues.
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Aminoglycoside Antibacterial
Controlled Drug Substance
NO
Indications and Purpose
What is gentamicin?
Gentamicin is an antibiotic used to treat serious bacterial infections. It belongs to the aminoglycoside class, which works by stopping bacteria from making proteins they need to grow. It's used for infections like those of the urinary tract, respiratory system, and skin. Gentamicin is often used in hospitals and is usually given by injection.How does gentamicin work?
Gentamicin works by stopping bacteria from making proteins they need to grow. It binds to bacterial ribosomes, which are structures that make proteins, and disrupts their function. This action kills the bacteria, helping to clear the infection. It's effective against a wide range of bacteria.Is gentamicin effective?
Gentamicin is effective in treating serious bacterial infections. It works by killing bacteria, which helps clear the infection. Clinical studies support its effectiveness for various infections, including those of the urinary tract, respiratory system, and skin. Your doctor will determine if gentamicin is appropriate for your specific condition.
Directions for Use
What is the usual dose of gentamicin?
The usual dose of gentamicin varies based on the infection being treated and the patient's kidney function. It's typically administered by injection. Your doctor will determine the appropriate dose and frequency for your specific condition. Always follow your doctor's dosing instructions carefully.How do I take gentamicin?
Gentamicin is usually given as an injection by a healthcare professional. The dose and frequency depend on your condition and response to treatment. It's important to follow your doctor's instructions carefully. If you miss a dose, contact your healthcare provider for advice. Do not double up on doses. Always follow your doctor's specific advice about diet and fluid intake while taking this medication.For how long do I take gentamicin?
Gentamicin is usually used for short-term treatment of acute infections. The duration depends on the type and severity of the infection. Your doctor will determine how long you need to take it. Always complete the full course as prescribed to ensure the infection is fully treated.How long does it take for gentamicin to start working?
Gentamicin starts working quickly, often within a few hours of administration. However, the full therapeutic effect may take a few days, depending on the infection's severity and location. Your doctor will monitor your progress to ensure the medication is working effectively.How should I store gentamicin?
Store gentamicin at room temperature, away from light and moisture. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.How do I dispose of gentamicin?
If you can, bring unused gentamicin to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, consult your pharmacist for advice on safe disposal.
Warnings and Precautions
Who should avoid taking gentamicin?
Gentamicin should not be used if you have a known allergy to it. Caution is needed in patients with kidney problems or hearing issues, as gentamicin can worsen these conditions. Always inform your doctor of your medical history before starting gentamicin.Can I take gentamicin with other prescription drugs?
Gentamicin can interact with other medications that affect kidney function or hearing, increasing the risk of side effects. Always inform your doctor about all medications you're taking. They can help manage potential interactions and adjust your treatment plan as needed.Can gentamicin be taken safely while pregnant?
Gentamicin is generally not recommended during pregnancy unless absolutely necessary. It can potentially harm the developing baby, particularly affecting the kidneys and hearing. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options.Can gentamicin be taken safely while breastfeeding?
Gentamicin can pass into breast milk, but the effects on a breastfed infant are not well-documented. If you're breastfeeding, talk with your doctor about the risks and benefits of using gentamicin. They can help determine the best treatment plan for you and your baby.Is gentamicin safe for the elderly?
Elderly patients are more vulnerable to the side effects of gentamicin, such as kidney damage and hearing loss. Careful monitoring is essential. Your doctor may adjust the dose based on kidney function and overall health. Always follow your doctor's advice when using gentamicin.Is it safe to exercise while taking gentamicin?
You can exercise while taking gentamicin, but be cautious. This medication can cause dizziness or balance issues, which might affect your ability to exercise safely. If you feel dizzy or unsteady, stop exercising and rest. Talk with your doctor if you have concerns about your specific situation.Is it safe to drink alcohol while taking gentamicin?
It's best to avoid alcohol while taking gentamicin. Alcohol can increase the risk of kidney damage and may worsen side effects like dizziness. If you choose to drink, limit your intake and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking gentamicin.What are the most common side effects of gentamicin?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of gentamicin include kidney damage and hearing loss. These effects are serious and require monitoring. If you notice new symptoms after starting gentamicin, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.Does gentamicin have adverse effects?
Adverse effects are unwanted reactions to a medication. Gentamicin can cause kidney damage and hearing loss, which are serious side effects. Less common effects include dizziness and balance issues. If you notice any new or worsening symptoms while taking gentamicin, contact your doctor immediately. Regular monitoring helps manage these risks.Is gentamicin addictive?
Gentamicin is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. It works by killing bacteria and doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.Does gentamicin have any safety warnings?
Yes, gentamicin has important safety warnings. It can cause kidney damage and hearing loss, especially with high doses or prolonged use. Monitoring kidney function and hearing is essential during treatment. If you experience symptoms like ringing in the ears or changes in urine output, contact your doctor immediately. Adhering to safety warnings helps prevent serious side effects.Is it safe to stop gentamicin?
Gentamicin is usually used for short-term treatment of infections. Stopping it early can lead to incomplete treatment and resistance. Always complete the full course as prescribed by your doctor. If you have concerns about side effects, talk with your doctor before stopping the medication.