Chronic Hepatitis C
Ledipasvir and sofosbuvir are used to treat chronic hepatitis C, which is a long-term viral infection affecting the liver. This combination is effective against different types of the virus, helping to clear the infection and prevent liver damage. The goal of the treatment is to achieve a sustained virologic response, meaning the virus becomes undetectable in the blood.
Ledipasvir works by blocking a protein the hepatitis C virus needs to multiply, while sofosbuvir interferes with the virus's genetic material, stopping it from growing. Together, they reduce the amount of virus in the body, helping the immune system to clear the infection. This dual action makes them a powerful treatment option for hepatitis C.
The usual adult daily dose for ledipasvir and sofosbuvir is one tablet taken once a day. Each tablet contains 90 mg of ledipasvir and 400 mg of sofosbuvir. This fixed-dose combination is designed to be taken together to maximize effectiveness. It's important to take the medicine exactly as prescribed by the healthcare provider to ensure the best results.
Common side effects of ledipasvir and sofosbuvir include tiredness, headache, and nausea. These effects are generally mild and manageable. Significant adverse effects are rare but can include serious allergic reactions, which may present as rash, itching, or swelling. It's important to monitor for any unusual symptoms and report them to a healthcare provider.
Important warnings include the risk of serious allergic reactions and potential drug interactions. Patients with severe liver or kidney problems should use these medicines with caution. It's contraindicated in patients allergic to any ingredients. Both medicines require careful monitoring in patients with other medical conditions. Inform the healthcare provider of all medical history and current medications to avoid complications.
US(FDA)
YES
NO
Hepatitis C Virus NS3/4A Protease Inhibitor, Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor
NO