prednisone
ENGLISH
Synonyms
Approved Treatment Indication:
Allergic Rhinitis, Pulmonary Tuberculosis, Atopic Dermatitis, Psoriatic Arthritis, Ulcerative Colitis, Contact Dermatitis, Seborrheic Dermatitis, Allergic Conjunctivitis, Multiple Sclerosis, Systemic Lupus Erythematosus, Idiopathic Thrombocytopenic Purpura, Ankylosing Spondylitis, Asthma, Collagen Diseases, Hypercalcemia, Inflammation, Leukemia, Erythema Multiforme, Lymphoma, Pemphigus, Thyroiditis, Synovitis, Autoimmune Hemolytic Anemia, Graft vs Host Disease, Adrenal Insufficiency, Berylliosis, Bursitis, Iritis, Dermatitis Herpetiformis, Nephrotic Syndrome, Rheumatic Diseases, Sarcoidosis, Serum Sickness
Summary
What conditions Prednisone is used for
Prednisone is used to treat conditions like arthritis, which is joint inflammation, asthma, which is a lung condition causing breathing difficulty, and allergies, which are reactions to substances like pollen or dust. It helps reduce inflammation and suppresses the immune system to relieve symptoms.
How Prednisone works in the body
Prednisone works by mimicking cortisol, which is a hormone that reduces inflammation and suppresses the immune system. It decreases the production of substances that cause inflammation, helping to relieve symptoms like pain and swelling.
The usual dosages and routes of administration of Prednisone
The usual starting dose of Prednisone for adults ranges from 5 mg to 60 mg per day, depending on the condition. It's often taken once daily, usually in the morning, with food to prevent stomach upset. Always follow your doctor's specific dosing instructions.
The most commonly observed adverse effects of Prednisone
Common side effects of Prednisone include increased appetite, which can lead to weight gain, mood changes like anxiety, and increased blood sugar levels. These effects vary among individuals and are usually mild to moderate.
Important safety warnings and contraindications of Prednisone
Prednisone can weaken the immune system, increasing infection risk. Long-term use may lead to bone loss and high blood pressure. It should not be used if you have a fungal infection, as it can worsen the condition. Always consult your doctor about your medical history before starting Prednisone.
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Corticosteroid
Controlled Drug Substance
NO
Indications and Purpose
What is Prednisone?
Prednisone is a corticosteroid medication that reduces inflammation and suppresses the immune system. It's used to treat conditions like arthritis, asthma, and allergies. It works by mimicking cortisol, a hormone that reduces inflammation. Prednisone is often used with other therapies to manage symptoms effectively.How does Prednisone work?
Prednisone works by mimicking cortisol, a hormone that reduces inflammation and suppresses the immune system. It decreases the production of substances that cause inflammation, helping to relieve symptoms like pain and swelling. This makes it effective for conditions like arthritis and asthma.Is Prednisone effective?
Yes, Prednisone is effective for reducing inflammation and suppressing the immune system. It's used to treat conditions like arthritis, asthma, and allergies. Clinical studies support its effectiveness in managing these conditions. However, its effectiveness can vary based on the condition being treated and individual response.
Directions for Use
What is the usual dose of Prednisone?
The usual starting dose of Prednisone for adults varies based on the condition being treated. It can range from 5 mg to 60 mg per day. The dose is often adjusted based on response and side effects. For children and the elderly, doses are carefully monitored and adjusted. Always follow your doctor's specific dosing instructions for your health needs.How do I take Prednisone?
Take Prednisone exactly as your doctor prescribes. It's usually taken once daily, often in the morning, with food to prevent stomach upset. You can crush the tablet if needed. If you miss a dose, take it as soon as you remember, unless it's close to your next dose. In that case, skip the missed dose. Don't take two doses at once. Avoid alcohol and follow any specific dietary advice from your doctor while on this medication.For how long do I take Prednisone?
Prednisone is used for both short-term and long-term treatment, depending on the condition. For acute symptoms, it might be used for a few days to weeks. For chronic conditions, it could be long-term. Your doctor will determine the duration based on your response and health needs. Always follow your doctor's instructions.How long does it take for Prednisone to start working?
Prednisone starts working quickly, often within a few hours. Full effects can be seen in a few days, depending on the condition. Factors like dosage and individual response can affect how quickly you notice improvements. Always take Prednisone as prescribed for the best results.How should I store Prednisone?
Store Prednisone at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms. Always keep it out of reach of children. Check the expiration date regularly and dispose of any unused or expired medication properly.How do I dispose of Prednisone?
Dispose of unused Prednisone by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
Warnings and Precautions
Who should avoid taking Prednisone?
Prednisone should not be used if you have a fungal infection, as it can worsen the condition. Caution is needed if you have diabetes, high blood pressure, or osteoporosis, as Prednisone can exacerbate these conditions. Always consult your doctor about your medical history before starting Prednisone to ensure it's safe for you.Can I take Prednisone with other prescription drugs?
Prednisone can interact with several medications, increasing the risk of side effects. For example, it can interact with blood thinners, increasing bleeding risk, and with diabetes medications, affecting blood sugar control. Always inform your doctor about all medications you're taking to avoid interactions and ensure safe treatment.Can Prednisone be taken safely while pregnant?
Prednisone is generally considered safe during pregnancy, but it should be used only if the benefits outweigh the risks. It can cross the placenta, so your doctor will weigh the potential effects on the baby. Always discuss with your doctor if you're pregnant or planning to become pregnant while on Prednisone.Can Prednisone be taken safely while breastfeeding?
Prednisone is generally safe to use while breastfeeding, but it can pass into breast milk. High doses may affect the baby, so your doctor will consider the benefits and risks. If you're breastfeeding, talk to your doctor about the safest way to use Prednisone and monitor your baby for any unusual symptoms.Is Prednisone safe for the elderly?
Elderly individuals are more vulnerable to Prednisone's side effects, like bone loss and high blood pressure. It's generally safe if monitored closely by a doctor. Regular check-ups are important to adjust the dose and manage any side effects. Always discuss your health conditions with your doctor before starting Prednisone.Is it safe to exercise while taking Prednisone?
Yes, you can exercise while taking Prednisone, but be cautious. Prednisone can cause muscle weakness and joint pain, which might affect your exercise capacity. Stay hydrated and avoid high-impact activities if you experience discomfort. Consult your doctor for personalized exercise advice while on Prednisone.Is it safe to drink alcohol while taking Prednisone?
It's best to limit alcohol while taking Prednisone. Alcohol can increase the risk of stomach irritation and ulcers, which are potential side effects of Prednisone. If you choose to drink, do so in moderation and watch for symptoms like stomach pain or nausea. Always consult your doctor for personalized advice.What are the most common side effects of Prednisone?
Side effects are unwanted reactions to a medication. Common side effects of Prednisone include increased appetite, weight gain, and mood changes. These effects vary among individuals. If you experience new symptoms, they might be temporary or unrelated to Prednisone. Always talk to your doctor before stopping any medication.Does Prednisone have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Prednisone include weight gain, mood changes, and increased blood sugar. Serious effects can include high blood pressure and bone loss. If you notice any new or worsening symptoms, contact your doctor. They can help manage these effects and adjust your treatment if necessary.Is Prednisone addictive?
Prednisone is not addictive in the traditional sense, but it can cause physical dependence. This means your body may rely on it, and stopping suddenly can lead to withdrawal symptoms like fatigue and body aches. To avoid dependence, follow your doctor's instructions and never stop Prednisone abruptly without medical guidance.Does Prednisone have any safety warnings?
Yes, Prednisone has important safety warnings. It can weaken your immune system, increasing infection risk. Long-term use may lead to bone loss, high blood pressure, and eye problems. Not following these warnings can lead to serious health issues. Always follow your doctor's advice and report any unusual symptoms immediately.Is it safe to stop Prednisone?
Stopping Prednisone suddenly can be dangerous. It can cause withdrawal symptoms like fatigue and body aches. If you're using it for a chronic condition, stopping might worsen your symptoms. Always consult your doctor before stopping Prednisone. They may suggest gradually reducing your dose to avoid withdrawal and keep your condition under control.