rolapitant

ENGLISH

Synonyms

Approved Treatment Indication:

Nausea, Vomiting

Summary

  • What conditions Rolapitant is used for

    Rolapitant is used to prevent nausea and vomiting, which are common side effects of chemotherapy, a treatment for cancer that uses drugs to kill cancer cells.

  • How Rolapitant works in the body

    Rolapitant works by blocking NK1 receptors, which are parts of the brain that trigger nausea and vomiting, helping to prevent these symptoms during chemotherapy.

  • The usual dosages and routes of administration of Rolapitant

    The usual dose of Rolapitant for adults is 180 mg taken as a single dose before chemotherapy. It is taken orally, which means by mouth, and can be taken with or without food.

  • The most commonly observed adverse effects of Rolapitant

    Common side effects of Rolapitant include fatigue, which means feeling very tired, and dizziness, which is a sensation of spinning or losing balance.

  • Important safety warnings and contraindications of Rolapitant

    Do not take Rolapitant if you are allergic to it. Inform your doctor about all medications you are taking to avoid interactions. Avoid driving if you feel dizzy or drowsy after taking it.

Drug Status

Government Approvals

Government Approvals

US(FDA)

WHO Essential Medicine

WHO Essential Medicine

NO

Known Teratogen

Known Teratogen

NO

Pharmaceutical Class

Pharmaceutical Class

Substance P/Neurokinin-1 Receptor Antagonist

Controlled Drug Substance

Controlled Drug Substance

NO

Indications and Purpose

  • What is Rolapitant?

    Rolapitant is a medication used to prevent nausea and vomiting caused by chemotherapy. It works by blocking certain receptors in the brain that trigger these symptoms. Rolapitant is taken as a single dose before chemotherapy and is part of a class of drugs called NK1 receptor antagonists.
  • How does Rolapitant work?

    Rolapitant works by blocking NK1 receptors in the brain, which are involved in triggering nausea and vomiting. Think of it like turning off a switch that causes these symptoms. This helps prevent nausea and vomiting during chemotherapy, improving comfort and quality of life.
  • Is Rolapitant effective?

    Rolapitant is effective in preventing nausea and vomiting caused by chemotherapy. It works by blocking certain receptors in the brain that trigger these symptoms. Clinical studies show that Rolapitant significantly reduces the incidence of nausea and vomiting in patients undergoing chemotherapy.

Directions for Use

  • What is the usual dose of Rolapitant?

    The usual dose of Rolapitant for adults is 180 mg taken as a single dose before chemotherapy. It is not typically adjusted for children or the elderly. Always follow your doctor's specific dosing instructions for your personal health needs.
  • How do I take Rolapitant?

    Rolapitant is usually taken as a single dose before chemotherapy. It should be taken with or without food. Do not crush or chew the tablet. If you miss a dose, take it as soon as you remember, but do not double up on doses. Always follow your doctor's specific instructions regarding the timing and frequency of your medication.
  • For how long do I take Rolapitant?

    Rolapitant is usually taken as a single dose before chemotherapy to prevent nausea and vomiting. It is not typically used for long-term treatment. Always follow your doctor's instructions regarding the duration of use for your specific treatment plan.
  • How long does it take for Rolapitant to start working?

    Rolapitant begins working shortly after you take it, with effects lasting up to 120 hours. It is taken before chemotherapy to prevent nausea and vomiting. The full benefits are usually noticed during and after chemotherapy sessions. Always take it as prescribed for the best results.
  • How should I store Rolapitant?

    Store Rolapitant at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms. Always keep Rolapitant out of children's reach to prevent accidental swallowing.
  • How do I dispose of Rolapitant?

    Bring unused Rolapitant to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash.

Warnings and Precautions

  • Who should avoid taking Rolapitant?

    Do not take Rolapitant if you are allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Always inform your doctor about any allergies or other medications you are taking to avoid potential interactions.
  • Can I take Rolapitant with other prescription drugs?

    Rolapitant can interact with certain medications, increasing the risk of side effects or reducing effectiveness. Inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can help manage any interactions and adjust your treatment plan as needed.
  • Can Rolapitant be taken safely while pregnant?

    The safety of Rolapitant during pregnancy is not well-established. There is limited information on its use in pregnant women. If you are pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for managing nausea and vomiting.
  • Can Rolapitant be taken safely while breastfeeding?

    The safety of Rolapitant while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. If you are breastfeeding or planning to breastfeed, discuss with your doctor the best treatment options for managing nausea and vomiting.
  • Is Rolapitant safe for the elderly?

    The elderly may be more vulnerable to side effects of Rolapitant, such as dizziness or fatigue. It's important for older adults to be monitored closely while taking this medication. Always follow your doctor's advice and report any unusual symptoms.
  • Is it safe to exercise while taking Rolapitant?

    You can exercise while taking Rolapitant, but be cautious. This medication can cause dizziness or fatigue, which might affect your exercise capacity. To exercise safely, stay hydrated and watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest.
  • Is it safe to drink alcohol while taking Rolapitant?

    It's best to avoid alcohol while taking Rolapitant. Alcohol can increase the risk of side effects like dizziness or drowsiness. If you choose to drink, limit your intake and watch for any warning signs. Talk with your doctor about alcohol use while taking Rolapitant.
  • What are the most common side effects of Rolapitant?

    Side effects are unwanted reactions to a medication. Common side effects of Rolapitant include fatigue, dizziness, and hiccups. These effects vary from person to person. If you notice new symptoms after starting Rolapitant, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
  • Does Rolapitant have adverse effects?

    Adverse effects are unwanted reactions to a medication. Common adverse effects of Rolapitant include fatigue and dizziness. Serious side effects are rare but can include allergic reactions. If you experience any new or worsening symptoms, contact your doctor immediately.
  • Is Rolapitant addictive?

    Rolapitant is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by blocking certain receptors in the brain to prevent nausea and vomiting. It doesn't affect brain chemistry in ways that could lead to addiction.
  • Does Rolapitant have any safety warnings?

    Rolapitant has important safety warnings. It may interact with other medications, so inform your doctor about all drugs you are taking. Not adhering to safety warnings can lead to increased side effects or reduced effectiveness. Always follow your doctor's advice and report any unusual symptoms.
  • Is it safe to stop Rolapitant?

    Rolapitant is usually taken as a single dose before chemotherapy, so there is no ongoing use to stop. If you have concerns about your treatment plan, discuss them with your doctor. They can provide guidance on any changes to your medication regimen.

Forms / Brands

Medwiki empowers you with simple, useful health facts from trusted sources. We're not doctors—we don't diagnose, treat, or give medical advice. Always consult with your healthcare provider before making any medical decision.